Alex Karev became a beloved Grey’s Anatomy character through the years, but the suddenness of his departure from the medical drama made many wonder what was behind Justin Chambers’ exit from Grey’s Anatomy. How Alex Karev disappeared from Grey’s Anatomy made his exit one of if not the most controversial, which is no small feat for a TV show that for a long time killed off its main characters as Grey’s Anatomy’s earlier seasons predominantly did instead of letting them move on to greener pastures. In Alex Karev’s case, his exit storyline caused controversy because of what story it resumed.