2 weeks agoBlogsComments Off on Taliban bizarrely says elderly Brit couple were arrested over ‘misunderstanding’… but pair still haven’t been heard from
THE Taliban have bizarrely claimed the arrest of a British couple in Afghanistan was due to a “misunderstanding.”
Peter Reynolds, 79, and his wife Barbie, 75, were arrested on 1 February on their way back home to the Bamiyan province.
The Taliban said today that the couple were detained due to a “misunderstanding” that they had fake Afghan passports.
It comes after the group said on Monday was aiming to release the Brits “as soon as possible”.
Taliban official Abdul Mateen Qani told the BBC: “A series of considerations is being taken into account, and after evaluation, we will endeavour to release them as soon as possible.”
More to follow… For the latest news on this story keep checking back at The Sun Online
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While it’s unclear yet whether the retailer is set to shut down the website for good, prices have been slashed to as little as £2.60.
Shoppers can currently save big across jackets, dresses and knitwear, so it’s no surprise that pieces are selling out seriously fast.
To save fashion fans from endless scrolling through the site, we’ve rounded up the best live deals on the site right now, but we’re not expecting them to stay in stock for long.
Sweater vests are perfect for transitional dressing as they can be worn alone or layered with tops and blouses.
New Look’s on-trend version comes in three neutral tones to pair with everything from satin maxi skirts to jeans and blouses, featuring a round neck and side slits.
The knitted number is reduced by 50% making it just £10, but it’s already sold out in one colourway.
New Look Leather-Look Biker Jacket, £32.24 (was £42.99)
New Look’s leather-look jacket is 25% off
New Look Leather-Look Biker Jacket, £32.24 (was £42.99)
A classic trench coat is a must-have for any capsule wardrobe.
The lightweight design makes them ideal for throwing on over anything during the transitional seasons, and shoppers can save 25% on New Look’s version.
The double breasted design gives a smart finish, while the belted design will cinch the waist for a flattering finish.
It’s unclear how long New Look’s huge sale will be running for, but items are selling out seriously fast – so we recommend shopping your favourite finds soon.
2 weeks agoBlogsComments Off on ‘Groundbreaking’ new vaccine REVERSES cancer in patients with ‘fatal disease’
A GROUNDBREAKING cancer vaccine reversed the disease in nine patients, a study has shown.
All nine patients enrolled in a Yale University study testing out personalised treatments against advanced kidney cancer remained disease free three years after receiving doses.
GettyNine patients with advanced kidney cancer remained disease free after receiving personalised vaccines[/caption]
GettyThe vaccines trained immune cells to hunt down cancer cells lingering after surgery[/caption]
Each person’s vaccine was created by examining the DNA and RNA in their tumour, which identified individual mutations in each of their cancers that weren’t present in normal, healthy cells.
Like all vaccines, personalised cancer vaccines train the body’s immune system to hunt down and destroy a threat.
The nine participants had all received surgery to treat stage three or four kidney cancer.
So in their case, the threat their immune systems were being trained to detect were any cancer cells remaining after surgery.
The vaccine was able to snuff out lingering cancerous cells while avoiding healthy cells after being fine tuned to each patient’s biology.
Currently approved immune therapies for kidney cancer aim to “release the brakes” on the immune system to allow it to attack cancer cells, but they don’t tell the immune cells where to go.
As a result, some patients don’t see any benefits from the treatments, while others may experience side effects from an overactive immune system.
Dr David Braun, the study’s first author and researcher at the Yale Cancer Center, said: “The idea behind this trial was to specifically steer the immune system toward a target that is unique to the tumour.”
Kidney cancer is the sixth most common type of the disease in the UK, with around 13,800 new cases diagnosed every year.
In the trial, the personalised cancer jab was designed to sniff out and destroy specific mutated cells that drive tumour growth in patients with clear cell renal cell carcinoma (ccRCC).
Renal cell carcinoma accounts for 80 per cent of all kidney cancer types in UK, and ccRCC makes up about 80 per cent of these.
The standard treatment for patients with ccRCC is currently surgery to remove tumours, followed by immunotherapy with a targeted therapy to blast remaining cells.
However, many patients will see their cancer return, study authors noted, saying “there remains a high unmet clinical need to improve outcomes after surgery for patients with high-risk RCC”.
Dr Braun said: “For patients with high-risk ccRCC, we want to improve post-surgery treatment options that reduce the risk of the cancer coming back.”
Yale researchers conducted a phase I trial, which is used to assess whether a new treatment is safe or effective.
The nine patients received multiple doses of the personalised cancer vaccine. Four of them received just the vaccine, while the remaining five also had small doses of the immunotherapy drug ipilimumab.
Seven patients had stage three disease, and two had stage four kidney cancer.
All nine patients had an immune response to the vaccine within three weeks.
In seven of nine patients, those T cells were capable of recognising the patient’s tumour.
Cancer-fighting T cells remained elevated throughout the study and for years afterwards, researchers observed.
Dr Braun said: “This strong and durable activation in T cells was encouraging and indicates that we’re able to generate a long-lasting, anti-cancer immune response with the vaccine.”
While patients typically experienced flu-like symptoms for one to two days after their vaccinations, none experienced severe side effects.
Researchers also said there were no significant differences in outcomes between patients who received ipilimumab along with the jab and those who received the cancer vaccine.
While the trial’s results – published in the journal Nature – are promising, researchers said trials with more patients are needed to confirm the vaccine’s effectiveness and explore its full potential.
Dr Braun is currently conducting a phase II study with patients receiving a similar personalised cancer vaccine with the targeted therapy, Keytruda, also known as pembrolizumab.
Personalised cancer jabs are also being tested in the UK, with the NHSmatching patients to clinical trials for their specific tumours through its new Cancer Vaccine Launch Pad.
Jab maker BioNTech has signed a deal to enrol 10,000 UK patients on to cancer vaccine trials by 2030.
CANCER vaccines are an exciting prospect because they use the body’s own immune system to fight tumours, reducing the collateral damage to healthy cells which is a risk of surgery, radiotherapy and chemo.
Hopefully this will mean people can be treated for longer without the fear of crippling or even deadly side effects, improving their survival chances.
Research is still in the early stages so the number of patients who can try out the vaccines in the next couple of years is likely to be small.
They will probably also be very expensive, as there is a lot of to-ing and fro-ing between the clinic and lab as every vaccine is tailored to the individual patient.
But the NHS’ Cancer Vaccines Launch Pad will help pharmaceutical companies study and develop the vaccines, set up the NHS infrastructure for if they become routinely used in future – and offer hope for patients along the way.
BBCJames Bye is set to rake in a fortune following his exit from EastEnders[/caption]
GettyThe 41-year-old has signed up to celebrity video messaging platform Cameo[/caption]
BBCFans were left devastated as Martin Fowler tragically died following the The Vic explosion during last week’s live episode[/caption]
Viewers watched as Martin suffered a cardiac arrest after an iron beam crushed his legs following the explosion at the Queen Vic.
With the character’s popularity reaching an all-time high, James looks set to cash in on his Walford demise.
The Sun can reveal he’s signed up celebrity video messaging platform Cameo just days after his final EastEnders scenes.
James is charging fans a whopping £51 for a personalised message from him, which average a minute-and-a-half in duration.
The dad-of-four is also offering to promote businesses with an official endorsement from him – as prices start at £1,778.
A source said: “James signing up for Cameo at the height of his popularity is a no-brainer, it’s easy cash for him to make before his next acting role.
“He joined the platform on the week of his exit from EastEnders and has already been inundated with requests.”
According to his profile, James is willing to send fans a simple Happy Birthday message, as well as take on the role of agony uncle and offer advice or an inspirational pep talk.
He’ll play iconic Jane Austen hero Mr Darcy in the theatrical world premiere of Death Comes To Pemberley.
EastEnders' 40th anniversary cameos so far
With the 40th anniversary of EastEnders coming up, fans are looking forward to some more incredible cameos from iconic faces of Walford's past. But who have we had so far?
Tracy-Ann Oberman – Oberman returned as Chrissie Watts, a character she last played nearly two decades ago.
Paul Bradley – Bradley returned as Nigel Bates, a character he last played over 25 years ago.
Micheal French – French returned as David Wicks, a character he last played two decades ago.
Patsy Palmer – Palmer returned as Bianca Jackson, a character she last played in 2019.
Ricky Groves – Groves returned as Garry Hobbs, a character who has not been seen since 2009.
Cliff Parisi – Parisi returned as Minty Peterson, a character who was last seen on the square in 2010.
Ross Kemp – Kemp has returned to play Grant Mitchell, a character he first played in 1990. The BBC has described Kemp’s storyline as “explosive”. Kemp said it was an “absolute honour” to return to the show.
Other aspects of the EastEnders 40th anniversary celebration include: A wedding between fan favorites, A huge explosion at the Queen Vic, and A live interactive episode.
2 weeks agoNews 1Comments Off on Jetsetters scrambling to get hands on Penneys trolley travel backpack just €28 and it comes in two colours
TRAVEL fans are set to go wild for a trolley backpack in Penneys – and it comes in two colours.
The Trolley Travel Backpack has landed in stores across the country.
Jetsetters are set to love the new trolley backpack in Penneysprimark.com/en-ie/It comes in two coloursprimark.com/en-ie/
The wheel backpack has storage compartments, adjustable shoulder strap and an extendable handle.
It’s the perfect choice for city breaks and shopping getaways.
Shoppers can chose from a neutral camel colour or a classic black.
Penneys chiefs said the trolley backpack comes with multiple storage compartments, plus an extendable handle and wheels.
They said: “This neutral-toned trolley travel backpack combines style with functionality.
“Its colour is complemented by tonal zippers, creating a sophisticated look.
“The quilted front pocket adds texture, while multiple compartments help keep your belongings tidy.
“An extendable handle and wheels offer easy manoeuvrability, and padded shoulder straps provide carrying comfort.
“This backpack is designed to transition seamlessly from airport terminals to city explorations.
“It’s an ideal choice for weekend getaways or as a carry-on, aiming to make your travels smoother and more organised.”
The handy bag is a bargain €28 and its set to fly off the shelves.
Jetsetters are also rushing to Dunnes Stores to bag their new designer packing cubes.
The Carolyn Donnelly Eclectic Packing Cubes, costing €12, offer luxurious storage solutions on a budget.
For €12 you get three sizes in the pack – each with a lovely design on them.
They come in Carolyn’s trademark shades of green and pink, and feature stunning floral patterns and zip pockets.
You can choose from sizes small, medium and large.
Dunnes Stores bosses said: “Designed to keep your luggage neat and tidy, these packing cubes from Carolyn Donnelly help to separate your travel necessities.
“In a handy pack of three, each one is designed with a classic Eclectic pattern.
“Made from a soft cotton, they offer a lightweight yet durable storage solution.
“Brought to you by Irish designer Carolyn Donnelly, exclusively for Dunnes Stores”.
These packing cubes are game-changers when it comes to organising your clothes while travelling.
They have compartments that help you neatly pack and separate your clothes in your luggage.
You can use them to categorise your clothes by colour, outfits or even by family member if you’re sharing a suitcase this summer.
They also help prevent wrinkles and save space in your luggage while travelling.
THE HISTORY OF PENNEYS
THE Penneys brand grew from humble beginnings on Dublin's Mary Street, where it opened its first store in 1969.
Known as Primark outside Ireland, the company was the brainchild of Garfield Weston, who hired Dubliner Arthur Ryan to make his vision reality.
Penneys branched into the UK in 1973 with its first store opening in Derby. The UK now has 191 Primark stores in total.
However, the Penneys name could not travel to Britain as the American retailer JC Penney had the right to use the name in the region.
And in 2006, the expansion into Europe began with an opening in Spain, followed by the Netherlands, Portugal, Germany, Belgium, Austria, France and Italy.
Primark went Stateside for the first time in September 2015, with the opening of a store in Boston. There are now 27 stores in America with branches in Florida, Brooklyn, Pennsylvania and New Jersey.
The retailer’s opened its largest store in Birmingham in 2019.
It spans five floors and features Primark’s biggest beauty studio to date, a barbers and three restaurants.
The compact bag is perfect to bring on boardprimark.com/en-ie/The travel bag is a bargain €28primark.com/en-ie/Shoppers will need to act quick to grab the bagGarrett White
2 weeks agoNews 1Comments Off on CPI-M to opt for complete decentralisation of campaign strategy in Bengal
Kolkata, Feb 25 (SocialNews.XYZ) The CPI-M in West Bengal will adopt the option of complete decentralisation of the party’s campaign strategy for the crucial Assembly elections in the state next year. This decentralisation strategy might...
2 weeks agoBioGraphiComments Off on Teachers should listen to both sides like lawyers do – Former GES boss advises
Following a violent clash between students and residents of a community, former Director General of the Ghana Education Service (GES), Charles Aheto-Tsegah, has urged parents to work closely with schools to maintain discipline among students. Speaking in an interview on Starr FM, Aheto-Tsegah emphasized the importance of communication between parents and school authorities when disciplinary […]
2 weeks agoBlogsComments Off on Fans rip Raiders over Pete Carroll’s airplane seat going to NFL Combine
NFL scouts and executives arrived in Indianapolis on Monday for the annual Scouting Combine at Lucas Oil Stadium. Among them was Las Vegas Raiders head coach Pete Carroll, whose flight from Seattle was quickly noted on social media, with even details like his seat location making the rounds online. According to Sports Illustrated’s Grant Cohn, […]
